Philly Sigue Amando
Without worrying about HIV
Sex. Your way.

How do you love, Philly? Is it a serious thing or a one night fling? Either way, you deserve HIV protection that doesn’t interfere with how you choose to live your life. PrEP is a once daily pill that has the power to keep your sex life HIV-free.

PrEP Any Time
PrEP works
over 90% of the time.
So you can work it,


Yep, you read that right. PrEP is over 90% effective at preventing HIV when taken daily. It doesn’t matter how many partners you have or what you get up to together—you’re protected.

Don’t forget that PrEP does not protect from other STIs or unintended pregnancies so be sure to wear a condom.

Prevention has
never been


While today’s HIV treatments are more effective than ever, prevention is still the best way to avoid lifelong health risks associated with HIV. PrEP gives you this protection, plus the added flexibility to enjoy your sex life without worrying about HIV.

30,000 Horizontal dotted green line
people are estimated to be living with HIV in the greater Philadelphia Region
Philadelphia has an HIV rate that is
4x THE NAT’L AVERAGE Horizontal dotted purple line
62% Horizontal dotted blue line
of new HIV infections occur in persons under the age of 35


right for you?

Only you and a doctor can say for sure, but you can take this confidential quiz to get a better idea now.

No judgement
To make a decision about PrEP, you’ll need to be 100% open with how you live and how you love—and you can’t do that without a doctor you’re comfortable with. That’s why we’ve partnered with medical professionals that understand your sexuality, your identity, and your health needs.
Once you’ve partnered with a doctor you can trust, you can go over the many ways PrEP will affect you, including:
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Loving on a budget? Don’t worry. PrEP is covered by almost all insurance plans, including Medicaid.
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Side Effects
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Stomach pain, headaches and weight loss may occur, but according to most users, it’s minor and lasts only a few weeks.
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Whether it's hormone therapy or birth control, be assured PrEP won't interfere with their effectiveness.
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All Facts. No Judgement.

Find a doctor who will understand you.

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Helpline Dotted Line OR  Call the Health Information Helpline  215-985-2437
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OR  Call the Health Information Helpline  215-985-2437
Get Condoms Icon Stay protected with free condoms.

Whether or not PrEP is right for you, we want you to keep on loving. Stay safe and sexy with some extra protection.

Get Condoms
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Get Tested Icon Get tested for HIV and STIs.

Knowing your status is crucial to maintaining a healthy sex life. Not only is it easy and painless to get tested, it’s the right thing to do.

Get Tested

For in-person testing, visit

Health Center #1, 1930 S Broad St


Never be afraid to bring them up with your doctor. They’ve heard it all—including these common questions you can ask at your next appointment:

If you take PrEP every day, your chances of getting HIV from sex drop by over 90%. If you inject drugs, your risk for HIV drops by over 70%. Add condoms and other HIV prevention methods if you want even more protection!

No. Vaccines are only given one or twice before your body learns to fight off the infection for years. Unfortunately,  PrEP does not work that way. You must take it daily for full effectiveness, and if you stop, so does the protection.

Think of it like this: PrEP is like birth control, and PEP is like the morning after pill. Both can help prevent HIV, but they’re used very differently. PrEP is a daily pill that keeps you HIV negative when exposed to the virus. Meanwhile, PEP is used only as an emergency pill. If you’ve been exposed to HIV and you’re not on PrEP, taking PEP within 72 hours of exposure will help you stay HIV negative.

PrEP can help keep anyone HIV negative, regardless of age, sexual preference, or gender identity. However, there are groups of people who may especially benefit from the protection PrEP brings. This includes people who forget to use condoms, bareback, have HIV+ partners, aren’t sure of their partner’s status, have multiple partners, or inject drugs. If that applies to you, we encourage you to visit a doctor to see if you meet the medical requirements to get on PrEP. This includes an HIV negative status, a weight of at least 77 lbs., healthy kidneys, healthy bones, and a healthy liver.

PrEP is an excellent option for anybody who parties. Unlike using condoms, which require good judgment at the time of sex, you can take PrEP and get protected long before you’re in the heat of the moment. There are also no negative health interactions between PrEP, alcohol, weed and other party drugs. Please note though that PrEP’s effectiveness may decrease if you inject drugs, however, your risk for HIV is still reduced by over 70% in these situations—a significant level of protection that can make all the difference.

No sexual side effects have been reported from PrEP users. Many people even say they enjoy not having to worry about HIV during sex!

The most common side effects include headaches, stomach pain, and weight loss. However, the majority of people who take PrEP and experienced side effects say they only last for a couple of weeks. It’s rare but possible that you may experience kidney and bone issues, but once you’re on PrEP, your provider will regularly check these areas to catch anything before it becomes a problem.

The CDC reports that those who have taken PrEP for up to five years show no significant changes in their health. This may be in part to the regular checkups that come with taking PrEP. You may have heard Truvada, the medicine in PrEP and HIV treatment, is associated with kidney and bone problems in HIV+ people, but these side effects are not significant in HIV negative people with no previous history of these issues.

No need to worry—there’s no risk of PrEP interacting or lowering the effectiveness of your hormones. Research shows that feminizing hormones, in particular, are not affected. We always recommend working with your doctor though to coordinate your PrEP usage with your hormone therapy.

Most insurance plans now cover PrEP—even Medicaid! However, PrEP is still an option even for those who are not insured. We’ll work with you to find assistance programs that can help cover the cost.